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  • Title: Intravenous infusions of ifosfamide/mesna and perturbation of warfarin anticoagulant control.
    Author: Hall G, Lind MJ, Huang M, Moore A, Gane A, Roberts JT, Cantwell BM.
    Journal: Postgrad Med J; 1990 Oct; 66(780):860-1. PubMed ID: 2129174.
    Abstract:
    We report three patients who had serious disturbance of anticoagulant control while receiving ifosfamide/mesna-containing cytotoxic chemotherapy in association with warfarin. In view of the likely biological potentiation of warfarin by ifosfamide/mesna, close monitoring of anticoagulant control should be performed during the co-administration of these drugs.
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