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  • Title: Interaction of peptides with graphene oxide and its application for real-time monitoring of protease activity.
    Author: Zhang M, Yin BC, Wang XF, Ye BC.
    Journal: Chem Commun (Camb); 2011 Feb 28; 47(8):2399-401. PubMed ID: 21305066.
    Abstract:
    We have developed a novel graphene-based biosensing platform using peptides as probe biomolecules, and demonstrated its feasibility in the application of real-time monitoring of protease activity based on FRET between GO and dye-labeled peptides. This assay allows the rapid and accurate determination of enzyme kinetic parameters as well as inhibition constants.
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