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  • Title: Prolyl hydroxylase and collagen biosynthesis in rat liver following varying degrees of partial hepatectomy.
    Author: Benjamin IS, Than T, Ryan S, Rodger MC, McGee JO, Blumgart LH.
    Journal: Br J Exp Pathol; 1978 Aug; 59(4):333-6. PubMed ID: 213093.
    Abstract:
    Prolyl hydroxylase activity and collagen biosynthesis have been measured at intervals following 2 extents of hepatic resection in rats. Prolyl hydroxylase activity is validated as a measure of collagen biosynthesis. The levels rise to a peak at 72 h and thereafter decline. The implications for the process of liver regeneration are discussed.
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