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  • Title: Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.
    Author: Josan JS, De Silva CR, Yoo B, Lynch RM, Pagel MD, Vagner J, Hruby VJ.
    Journal: Methods Mol Biol; 2011; 716():89-126. PubMed ID: 21318902.
    Abstract:
    The use of fluorescent (or luminescent) and metal contrast agents in high-throughput screens, in vitro assays, and molecular imaging procedures has rapidly expanded in recent years. Here we describe the development and utility of high-affinity ligands for cancer theranostics and other in vitro screening -studies. In this context, we also illustrate the syntheses and use of heteromultivalent ligands as targeted imaging agents.
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