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  • Title: Synthesis of graphene oxide-based biocomposites through diimide-activated amidation.
    Author: Shen J, Yan B, Shi M, Ma H, Li N, Ye M.
    Journal: J Colloid Interface Sci; 2011 Apr 15; 356(2):543-9. PubMed ID: 21329939.
    Abstract:
    In this work, a novel and facile method for covalent attachment of biomaterials to graphene oxide sheets (GOS) was developed. Four conjugates were obtained via the diimide-activated amidation reaction under ambient conditions. Final products were characterized by FT-IR spectroscopy, atomic force microscopy and transmission electron microscopy. Electrochemical characterization of the composite showed that the covalently bonded biomaterial retained its bioactivity. This method may provide a way for further preparation of graphene-based biodevices.
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