These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Molecular expansion of an individual coiled DNA on a graphite surface.
    Author: Wang H, Wang X, Li H, Zhang X, Zhang Y, Hu J.
    Journal: Langmuir; 2011 Mar 15; 27(6):2405-10. PubMed ID: 21341704.
    Abstract:
    Direct visualization and manipulation of a single polymer on a solid surface in fluid can greatly contribute to our understanding of polymer dynamics and physics relevant to many practical applications. In this paper, the authors report a novel phenomenon that a randomly coiled DNA molecule can be gradually expanded to form a spiral-like pattern by repeatedly rotating a water droplet on a graphite surface where the DNA molecule was deposited. The process of DNA expansion was traced using atomic force microscopy relocation imaging. A simple theoretical model based on the analysis of centrifugal and resistant forces exerted on the DNA molecule during the manipulation was presented to explain the formation of the spiral-like pattern. This study should provide us insight into the movement of polymers on a solid surface under fluid flow.
    [Abstract] [Full Text] [Related] [New Search]