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  • Title: Early recurrence is a predictor of late failure in surgical ablation of atrial fibrillation.
    Author: Maroto LC, Carnero M, Silva JA, Cobiella J, Pérez-Castellano N, Reguillo F, Pérez-Villacastín J, Rodríguez JE.
    Journal: Interact Cardiovasc Thorac Surg; 2011 May; 12(5):681-6. PubMed ID: 21343154.
    Abstract:
    We sought to determine if early recurrence of atrial fibrillation (AF) after surgical ablation is a risk factor of late failure. Between February 2004 to May 2009, 106 patients underwent surgical ablation of concomitant permanent AF with radiofrequency. Operations primarily consisted of valve surgery in 85% of patients. Hospital mortality was 2.8% (n = 3). The median follow-up was 37 months (interquartile rank 12-77), and was complete in 99% of patients. Freedom from AF was 82%, 76% and 68% at one, two and three years, respectively. Patients with early recurrence of AF had less prevalence of sinus rhythm in late follow-up (P < 0.001). Multivariate Cox regression analysis showed that AF duration [hazard ratio (HR) 1.014, 95% CI 1.009-1.020, P < 0.001] and early recurrence of AF (HR 3.45, 95% CI 1.50-7.95, P = 0.004) were independent risk factors for failure. In conclusion, in our series, early recurrence of AF after surgical ablation is a strong predictor of late failure.
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