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  • Title: Allopurinol hypersensitivity syndrome with acute generalized exanthematous pustulosis manifestations.
    Author: Teo WL, Pang SM, Koh HY.
    Journal: Cutan Ocul Toxicol; 2011 Sep; 30(3):243-4. PubMed ID: 21345152.
    Abstract:
    Allopurinol hypersensitivity syndrome(AHS) is a severe form of cutaneous adverse reaction that is associated with significant morbidity and mortality. We report a case of AHS with the cutaneous manifestation of acute generalised exanthematous pustulosis(AGEP). A 47 year old gentleman, with no previous skin disease, presented with a generalized mildly pruritic erythematous rash on the trunk and all 4 limbs, with patches of superficial non-follicular pustules. Our patient fulfilled both criteria for AGEP and AHS.
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