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  • Title: Cytotoxic triterpenoid saponins from the rhizomes of Anemone taipaiensis.
    Author: Wang XY, Chen XL, Tang HF, Gao H, Tian XR, Zhang PH.
    Journal: Planta Med; 2011 Sep; 77(13):1550-4. PubMed ID: 21347998.
    Abstract:
    Two new oleanane-type triterpenoid saponins, 1 and 2, and a new natural product, 3, together with five known saponins, 4- 8, were isolated from the rhizomes of ANEMONE TAIPAIENSIS. Their structures were elucidated by extensive spectroscopic analysis and chemical evidences. Six saponins, 1, 2, 4- 7, which possessed a free carboxylic group at C-28, exhibited significant cytotoxicity against human leukemia HL-60 cells and human hepatocellular carcinoma Hep-G2 cells with IC (50) values in the range of 1.31-10.12 µM.
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