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  • Title: [Combined analgetic drug treatment with ibuprofen after 3rd molar osteotomy].
    Author: Schmelzeisen R, Buchweitz IK, Fricke A, Frölich J.
    Journal: Dtsch Z Mund Kiefer Gesichtschir; 1990; 14(6):442-6. PubMed ID: 2135254.
    Abstract:
    In a placebo-controlled double-blind study using 3 x 400 mg ibuprofen during the surgical removal of impacted and dislocated third molars, a pain reduction of 64% (p = 0.05) as against the placebo control group could be demonstrated on the day of surgery and the first postoperative day. In view of the published results of a double-blind study on the reduction of cheek swelling using dexamethasone, the perioperative combination of 3 x 600 mg ibuprofen with 2 x 6 mg dexamethasone seems to be helpful in reliably preventing pain and swelling after dental surgery.
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