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  • Title: [Study on the alkaloids in the stems and leaves of Stephania cepharantha (II)].
    Author: He L, Zhang YH, Tang LJ, Song SH, Sun QY.
    Journal: Zhong Yao Cai; 2010 Oct; 33(10):1568-70. PubMed ID: 21355192.
    Abstract:
    OBJECTIVE: To study the alkaloids in the stems and leaves of Stephania cepharantha Hayata. METHODS: The dried stems and leaves of Stephania cepharantha Hayata were percolated with 95% ethanol and the solvent was removed by rotary evaporation to give a concentrate, and the concentrate was extracted by petroleum ether and chloroform. Column chromatograghy on MCI CHP 20P, silica gel, Rp-18, Sephadex LH-20 and polyamide were applied for the isolation and purification of the chloroform fraction. The structures were elucidated by their physicochemical properties and spectral data. RESULTS: Five alkaloids were obtained and identified as, Stephasunoline (I) Aknadinine (II), Discretamine (III), Acutumine (IV), Sinomenine (V). CONCLUSION: Compounds I, III, IV are isolated from this plant for the first time, and compound IV is isolated from the genus for the first time.
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