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  • Title: [Isolation of Toxoplasma gondii from the saliva of patients with acquired immunodeficiency syndrome (AIDS)].
    Author: Amato Neto V, Braz LM, Jamra LM, Higaki Y, Pasternak J.
    Journal: Rev Hosp Clin Fac Med Sao Paulo; 1990; 45(4):171-2. PubMed ID: 2135828.
    Abstract:
    Toxoplasma gondii has been found in saliva of patients with toxoplasmosis. We tried to isolate parasites in saliva in patients with AIDS. As it is known, the finding of antitoxoplasma antibodies is not useful for diagnosis of cerebral abscess in toxoplasmosis occurring in AIDS patients in Brazil where 90% or more adults have serological evidence of past infection with Toxoplasma gondii. In 26 patients with AIDS, including six with tomographical evidence suggesting cerebral abscess caused by Toxoplasma gondii, no parasites were found in the saliva by the use of the mouse inoculation model. This trial that the search for Toxoplasma gondii in the saliva is not an alternative method for the diagnosis of toxoplasmosis in patients with AIDS. Toxoplasma gondii has been found in the saliva of patients with toxoplasmosis. The authors attempted to isolate parasites from the saliva of those patients with AIDS. As it is known, the finding of antitoxoplasma antibodies is not useful for the diagnosis of cerebral abscess in toxoplasmosis occurring in AIDS patients in Brazil, where 90% or more of the adults have serological evidence of past infection with Toxoplasma gondii. In 26 patients with AIDS, including 6 with tomographical evidence suggesting cerebral abscess caused by Toxoplasma gondii, no parasites were found in the saliva through the use of the mouse inoculation model. This trial indicates that the search for Toxoplasma gondii in saliva is not an alternative method for the diagnosis of toxoplasmosis in patients with AIDS. (author's modified)
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