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  • Title: Psychiatric symptoms associated with Alzheimer's disease.
    Author: Mendez MF, Martin RJ, Smyth KA, Whitehouse PJ.
    Journal: J Neuropsychiatry Clin Neurosci; 1990; 2(1):28-33. PubMed ID: 2136060.
    Abstract:
    A retrospective chart review was undertaken to assess the prevalence of specifically defined psychiatric symptoms in 217 outpatients with clinically probable Alzheimer's disease. A weak but significant correlation was found between Alzheimer's disease and suspiciousness and paranoia (reported by 35.5% of patients), delusions (30%), and formed visual hallucinations (18.4%). Mild depressive symptoms, such as sad affect, hopelessness, and helplessness were reported by 40.6% of patients, anxiety and fearfulness by 30.9%, and aggressive acts by 24.9%. Psychotropic medications used to manage these symptoms included antipsychotics, in 11.5% of patients, anxiolytics, in 9.2%, and antidepressants, in 7.4%.
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