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  • Title: Leaf essential oil of Manekia naranjoana (Piperaceae) from Costa Rica and its cytotoxic activity.
    Author: Chaverri C, Díaz C, Cicció JF.
    Journal: Nat Prod Commun; 2011 Jan; 6(1):145-8. PubMed ID: 21366067.
    Abstract:
    The chemical composition of the leaf oil of Manekia naranjoana (C. DC.) Callejas (Piperaceae) from Costa Rica was analyzed by capillary GC/FID and GC/MS. Fifty-five compounds were identified. Major compounds from the leaf oil were beta-pinene (30.6%), alpha-pinene (18.8%), limonene (13.7%), and beta-caryophyllene (6.1%). The oil presented very low toxicity to tumor and non-tumor cell lines, even though it contains components, such as alpha- and beta-pinene, limonene and others, which have been shown to be cytotoxic. This is the first report of the chemical composition of the essential oil obtained from this species.
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