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  • Title: Myeloid differentiation factor 88 gene is involved in antiviral immunity in grass carp Ctenopharyngodon idella.
    Author: Su J, Dong J, Huang T, Zhang R, Yang C, Heng J.
    Journal: J Fish Biol; 2011 Mar; 78(3):973-9. PubMed ID: 21366589.
    Abstract:
    A full-length MyD88 cDNA (CiMyD88) was cloned and characterized from grass carp Ctenopharyngodon idella. CiMyD88 was found to be broadly expressed and was up-regulated by grass carp reovirus (GCRV) and CiMyD88 transcripts in vitro were rapidly elevated in C. idella kidney (CIK) cells after challenge with poly(I:C). These results suggest that CiMyD88 may be involved in the antiviral immune defence in C. idella.
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