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  • Title: Segmental dilatation of sigmoid colon in a neonate: atypical presentation and histology.
    Author: Mahadevaiah SA, Panjwani P, Kini U, Mohanty S, Das K.
    Journal: J Pediatr Surg; 2011 Mar; 46(3):e1-4. PubMed ID: 21376178.
    Abstract:
    Segmental dilatation of the colon is a rare disorder of colonic motility in children, often presenting with severe constipation in older infants, children, and occasionally adults. It may mimic the commoner Hirschsprung disease clinicoradiologically but differs in that the ganglion cell morphology and distribution are typically normal in the colon. We report a neonate with segmental dilatation of the sigmoid colon who had an atypical clinical presentation and describe certain abnormalities in bowel histology (hypertrophied muscularis propria, nerve plexus, and ganglion cells located within the circular layer rather than the normal myenteric location), for the first time in the English literature.
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