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  • Title: Differentiating pacemaker-mediated tachycardia from tachycardia due to atrial tracking: utility of V-A-A-V versus V-A-V response after postventricular atrial refractory period extension.
    Author: Ip JE, Markowitz SM, Liu CF, Cheung JW, Thomas G, Lerman BB.
    Journal: Heart Rhythm; 2011 Aug; 8(8):1185-91. PubMed ID: 21376834.
    Abstract:
    BACKGROUND: Dual-chamber pacemaker systems can lead to two forms of pacemaker-facilitated tachycardia: pacemaker-mediated tachycardia (PMT) and tracking of sinus or atrial tachycardia. Current pacemaker algorithms cannot always differentiate between these two tachycardias. OBJECTIVE: The purpose of this study was to investigate a novel algorithm for distinguishing the two mechanisms of pacemaker-facilitated tachycardia, which is based on the specific termination response to postventricular atrial refractory period (PVARP) extension. METHODS: We prospectively tested our algorithm using the Medtronic Virtual Interactive patient (VIP) II simulator (version 1.53) and a Medtronic Adapta ADDR01 dual-chamber pacemaker. RESULTS: Thirty-five scenarios that triggered "PMT detection" by the device were evaluated. All 12 scenarios of atrial tachycardias with intact AV conduction terminated with a Vp-Ar-Vs (V-A-V) response as a result of PVARP extension. Of the 11 scenarios of atrial tachycardia with complete heart block, all terminated with a Vp-Ar-As-Vp response. All four episodes of PMT with intact AV conduction terminated with a Vp-Ar-As-Vs (V-A-A-Vs) response. Of the eight episodes of PMT with complete heart block, all terminated with a Vp-Ar-As-Vp response. CONCLUSION: In the presence of intact AV conduction, the V-A-V response to PVARP extension is specific to atrial (or sinus) tachycardia, whereas the V-A-A-Vs response is specific to PMT. Recognizing the difference between the two forms of pacemaker-facilitated tachycardias has important implications for pacemaker programming.
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