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  • Title: A new synthesis of pyrazoles through a Lewis acid catalyzed union of 3-ethoxycyclobutanones with monosubstituted hydrazines.
    Author: Shan G, Liu P, Rao Y.
    Journal: Org Lett; 2011 Apr 01; 13(7):1746-9. PubMed ID: 21381639.
    Abstract:
    A new efficient and convenient approach toward the synthesis of pyrazoles is described. Through a Lewis acid catalyzed union of 3-ethoxycyclobutanones with monosubstituted hydrazines, a variety of pyrazole derivatives were prepared readily at ambient temperature with complete regioselectivity.
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