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  • Title: [Arteriolar circulation and arterial pressure in patients with essential hypertension].
    Author: Volkov VS, Rudenko EV, Vinogradova TS, Poseliugina OB.
    Journal: Klin Med (Mosk); 2010; 88(6):24-6. PubMed ID: 21395023.
    Abstract:
    Arteriolar circulation and its relationship with arterial pressure were studied in 127 patients with essential hypertension and 63 healthy subjects using continuous US dopplerography of the microcirculatory system at rest. Linear arteriolar blood flow rate was measured in healthy subjects and 47 patients before and after primary indapamide therapy. It was found to equal 17.7 (mean 9.1) cm/s in systole and 8.7 cm/s in diastole in the patients versus 12.2 (7.3) and 4.3 respectively in the healthy subjects (p = 0.005) giving indirect evidence of narrowed diameter of arterioles. Arteriolar circulation was shown to depend on the duration of arterial hypertension. Both AP and linear arteriolar blood flow rate decreased under effect of hypotensive therapy but there was no significant correlation between the two parameters.
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