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  • Title: Newly identified prions in budding yeast, and their possible functions.
    Author: Crow ET, Li L.
    Journal: Semin Cell Dev Biol; 2011 Jul; 22(5):452-9. PubMed ID: 21397710.
    Abstract:
    Yeast prions are atypical genetic elements that are transmitted as heritable protein conformations. [PSI+], [URE3], and [PIN+] are three well-studied prions in the budding yeast, Saccharomyces cerevisiae. In the last three years, several additional prions have been reported in yeast, including [SWI+], [OCT+], [MCA], [GAR+], [MOT3+], [ISP+], and [NSI+]. The growing number of yeast prions suggests that protein-based inheritance might be a widespread biological phenomenon. In this review, we summarize the characteristics of each prion element, and discuss their potential functional roles in yeast biology.
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