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  • Title: [Polymorphism of 17 Y-STR loci in Shanxi Han population and genetic relationship with 13 populations].
    Author: Shi MS, Bai RF, Fu B.
    Journal: Yi Chuan; 2011 Mar; 33(3):228-38. PubMed ID: 21402530.
    Abstract:
    To investigate the genetic polymorphisms of 17 Y-chromosomal short tandem repeats (Y-STR) loci in Shanxi Han population and to explore their forensic application values and genetic relationship with neighboring populations, 17 Y-STR in 222 unrelated healthy Shanxi Han individuals were amplified with Y-filerTM System, and the PCR products were detected with 3130 Genetic Aanalyzer. The allele frequencies and haplotype diversity were calculated. Y-STR data of another 13 populations were collected from publications. Cluster analysis and phylogenic trees were applied to show the genetic distance among the populations. As a result, a total of 219 haplotypes were identified, and the observed haplotypes diversity value was 0.9999. The gene diversity values (GD) for each locus ranged from 0.3894 (DYS391) to 0.9755 (DYS385a/b). Comparing with 13 populations, the genetic distance between Shanxi and Jihei Han populations was the smallest (0.0001), while the genetic distance between Shanxi and Taiwan population was the largest (0.0152). The phylogenetic tree was similar to the results of clustering analysis. Multiplex detection of the 17 Y-STR loci revealed a highly polymorphic genetic distribution, which would be very powerful for establishing a Y-STR database, for population genetics and forensic practice.
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