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  • Title: [Leprosy in a chimpanzee].
    Author: Ishii N, Udono T, Fujisawa M, Idani G, Tanigawa K, Miyamura T, Suzuki K.
    Journal: Nihon Hansenbyo Gakkai Zasshi; 2011 Feb; 80(1):29-36. PubMed ID: 21404593.
    Abstract:
    Leprosy is suspected to develop after a long period of latency following infection with Mycobacterium leprae (M. leprae) during infancy, but definitive proof has been lacking. We found a rare case of leprosy in a chimpanzee (Pan troglodytes) born in West Africa (Sierra Leone) and brought to Japan around 2 years of age. At 31, the ape started exhibiting pathognomic signs of leprosy. Pathological diagnosis, skin smear, serum anti-phenolic glycolipid-I (PGL-I) antibody, and by PCR analysis demonstrated lepromatous leprosy. Single-nucleotide polymorphism (SNP) analysis verified the West African origin of the bacilli. This occurrence suggests the possibility of leprosy being endemic among wild chimpanzees in West Africa, potentially posing a zoonotic risk.
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