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  • Title: Palladium-catalyzed three-component transformation of homoallenols: a regio- and stereoselective route to 1,5-amino alcohols.
    Author: Aylward M, Coeffard V, Guiry PJ.
    Journal: J Org Chem; 2011 May 06; 76(9):3536-8. PubMed ID: 21405098.
    Abstract:
    A palladium-catalyzed three-component transformation of enantioenriched homoallenols with aryl halides and amines has been developed to selectively afford (Z)-configured 1,5-amino alcohols in good-to-excellent yields without any epimerization.
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