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  • Title: An iminocoumarin-Cu(II) ensemble-based chemodosimeter toward thiols.
    Author: Jung HS, Han JH, Habata Y, Kang C, Kim JS.
    Journal: Chem Commun (Camb); 2011 May 14; 47(18):5142-4. PubMed ID: 21409269.
    Abstract:
    An 'ensemble'-based fluoregenic chemodosimeter 1-Cu(II) for detection of thiols is reported. Complex 1-Cu(II) sensitively senses thiols followed by hydrolysis to give a marked fluorescence enhancement over other amino acids at pH 7.4 under aqueous media. Confocal microscopic imaging of complex 1-Cu(II) is also herewith demonstrated for cellular thiol detection in HepG2 cells.
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