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  • Title: Management of low cardiac output syndrome after cardiac surgery using enoximone.
    Author: White DA, Latimer RD, Oduro A.
    Journal: Anaesthesia; 1990 May; 45(5):386-9. PubMed ID: 2141451.
    Abstract:
    This case report describes the use of enoximone, a potent phosphodiesterase F-IV inhibitor with inotropic and vasodilator actions, to treat low output syndrome after cardiac surgery. The reduced cardiac output was unresponsive to a combination of inotropic drugs and intra-aortic balloon counterpulsation was contraindicated. Cardiac output was increased dramatically by enoximone, but systemic vascular resistance and perfusion pressure remained low until the addition of metaraminol.
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