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  • Title: [The analgesic effect of plexus anesthesia with buprenorphine in patients].
    Author: Li B, Chen XL, Sun CC, Lü GY.
    Journal: Zhonghua Yi Xue Za Zhi; 2011 Feb 01; 91(5):334-6. PubMed ID: 21419010.
    Abstract:
    OBJECTIVE: To study the anesthetic effect of brachial plexus block by adding buprenorphine in local anesthetics and patients with intramuscular injection, and observe the anesthesia effects, the anesthesia maintenance time, postoperative analgesia effects. METHODS: 60 cases of upper limb to line, hand surgery patients from Sep. 2009 to Dec. 2009 in Tianjin Hospital were randomly divided into 3 groups. A (local anesthetics without buprenorphine, n = 20); B group (plus 2 µg/kg buprenorphine in local anesthetics, n = 20); C group (intramuscular injection 2 µg/kg buprenorphine before anesthesia, n = 20). With B/BRAMN-STIMMPLEX-DIG nerve stimulator guided positioning of brachial plexus block of axillary line. 3 groups of patients recorded (1) the onset time of narcotic; (2) the duration of anesthesia; (3) the surgery time; (4) the pain score of postoperative 4, 8, 12, 24, 36, 48, 72 h; (5) the incidence of nausea and vomiting; (6) observed other side effects. RESULTS: the patients' age, weight, sex, operation time of the 3 groups had no significant difference between the comparison (P > 0.05); anesthesia onset time between the 3 groups showed no significant difference (P > 0.05). Duration of anesthesia: A, C group was significantly shorter than the B group (P < 0.01); pain score at 4 h, A and B, C no significant difference between groups (P > 0.05); 8, 12, 24 h, when group A was significantly higher than the B, C group (P < 0.01), 36, 48, 72 h when the A group and B, C no significant difference between groups (P > 0.05); the incidence of nausea A group 10%, B group 20%, C group 20%. Vomiting, the incidence of A, B group was 0, C group 30%. CONCLUSION: Buprenorphine adding local anesthetics in brachial plexus block or intramuscular injection buprenorphine before a block can be to achieve a satisfactory effect of postoperative analgesia, buprenorphine adding local anesthetics in brachial plexus block Narcotic maintenance of anesthesia time can be extended and have a significant effect and fewer adverse reactions.
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