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  • Title: [Intra-arterial chemotherapy of the liver].
    Author: Tuchmann A.
    Journal: Wien Med Wochenschr; 1990 Apr 30; 140(8):195-9. PubMed ID: 2141964.
    Abstract:
    Hepatic artery infusion chemotherapy was introduced to treat non-resectable liver metastases or tumors. Although growth patterns of hepatic metastases and pharmacokinetics of cytostatics are well known, the response rate to intraarterial chemotherapy amounts to a maximum of 50% only, the mean survival time being 1 year or less. Until now, complete healing was not observed. Future efforts should be directed at increasing the response rate, decreasing regional adverse side effects and avoiding extrahepatic disease.
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