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  • Title: Aldose reductase C-106T gene polymorphism is associated with diabetic retinopathy in Japanese patients with type 2 diabetes.
    Author: Katakami N, Kaneto H, Takahara M, Matsuoka TA, Imamura K, Ishibashi F, Kanda T, Kawai K, Osonoi T, Matsuhisa M, Kashiwagi A, Kawamori R, Shimomura I, Yamasaki Y.
    Journal: Diabetes Res Clin Pract; 2011 Jun; 92(3):e57-60. PubMed ID: 21420193.
    Abstract:
    It is likely that the C allele of the polymorphism at position -106 in the promoter of aldose reductase gene, which codes a rate-limiting enzyme of the polyol pathway, is a susceptibility allele for diabetic retinopathy in Japanese type 2 diabetic patients.
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