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  • Title: Inflammatory fibroid polyp associated with early gastric carcinoma: a case report.
    Author: Mucientes P, Mucientes F, Klaassen R.
    Journal: Ann Diagn Pathol; 2012 Apr; 16(2):148-51. PubMed ID: 21439872.
    Abstract:
    Inflammatory fibroid polyp (IFP) is a rare mesenchymal lesion of the gastrointestinal tract. The association of IFP with gastric carcinoma has been only reported in 7 previously published cases. We present the case of a 69-year-old man who underwent gastrectomy because of an early gastric carcinoma invading the submucosa with an underlying IFP, which pushed the neoplastic surface to the gastric lumen in a polypoid fashion. The IFP revealed a CD34-positive spindle cell proliferation surrounding blood vessels in a concentric way and covered by carcinomatous glands. The patient is free of disease after 108 months of follow-up. The underlying spindle cell proliferation and blood vessels may be reactive to malignant glands found in the surface, although recent molecular analyses support the neoplastic nature of this lesion.
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