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  • Title: Acute megakaryoblastic leukemia in Down syndrome, following thrombocytopenia with antiplatelet antibody.
    Author: Sumi S, Obayashi M, Murakami M, Ito J, Okada N, Shibata Y.
    Journal: Tohoku J Exp Med; 1990 May; 161(1):65-7. PubMed ID: 2144373.
    Abstract:
    We report a case of acute megakaryoblastic leukemia (AMKL) with antiplatelet antibody in a boy with Down syndrome. When the patient was admitted, his platelet count was 1.3 X 10(4)/mm3 and antiplatelet antibody in the plasma was detected. Two months after admission, blasts, which showed positive reaction to both antiplatelet monoclonal antibody and platelet peroxidase, increased.
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