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  • Title: The use of Omegaven in treating parenteral nutrition-associated liver disease.
    Author: Park KT, Nespor C, Kerner J.
    Journal: J Perinatol; 2011 Apr; 31 Suppl 1():S57-60. PubMed ID: 21448206.
    Abstract:
    Parenteral nutrition (PN), containing fat emulsions derived from soybean, has been implicated in the progression of PN-associated liver disease and cholestasis, particularly in infants with short bowel syndrome. Clinical use of Omegaven, a parenteral fish-oil emulsion, has been shown in recent studies to be a promising therapy to reverse liver disease and cholestasis. This review summarizes the rationale, relevant clinical investigations and future direction of Omegaven therapy for PN-dependent infants.
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