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  • Title: Relapsing herpes simplex encephalitis resulting in Kluver-Bucy syndrome.
    Author: Ku BD, Yoon SS.
    Journal: Intern Med; 2011; 50(7):763-6. PubMed ID: 21467713.
    Abstract:
    Relapsing herpes simplex encephalitis (HSE) rarely occurs after acyclovir treatment. We treated a patient with relapsing HSE of the contralateral temporal lobe, resulting in Klüver-Bucy syndrome, after a full-dose acyclovir treatment. This case suggests that physicians should consider sudden behavioral and emotional changes after HSE treatment as a possible indication of relapsing HSE, as well as possible temporal lobe epilepsy, and the need to administer longer acyclovir treatment for select patients.
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