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  • Title: [Amplitude-time parameters of long-latency components (N1, N2 and P300) of acoustic evoked potential of healthy examinees of young and mature age].
    Author: Oknina LB, Kuznetsova OA, Belostostskiĭ AP, Nechaeva NL, Kutakova EV, Masherov EL, Romanov AS.
    Journal: Fiziol Cheloveka; 2011; 37(1):56-64. PubMed ID: 21469355.
    Abstract:
    The aim of study was to track a cumulative changes of amplitude-time parametres of components N1, N2 and P300 of acoustic evoked potential in experimental situations different in complexity (at the account and listening of sounds) and to compare the received distinctions at examinees of young and mature age. ERP were recorded at 12 healthy subjects from 18 to 22 ages and 12 subjects from 32 to 59 ages. The two-stimuli oddball paradigm was used. It is revealed that components N1, N2 and P300 recorded in the situation of the listenings of sounds without any preliminary instruction do not differ at persons of young and mature age. At examinees of younger age the biger amplitude of component N1 is noted at the account of sounds in comparison with listening whereas the latency of the one do not change depending on complexity of the task. It is shown that component N2 has stability of latency in relation to age and an experimental situation. The amplitude of component N2 is above at the account of sounds in both age groups. The amplitude-time parametres of component P300 do not differ at examinees of different age in a problem of listening of sounds. The revealed features of components N1, N2 and P300 at examinees of young and mature age in experimental situations different in complexity, allow to assume that with the years at the person adaptive mechanisms which allow carrying out successfully of the task.
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