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  • Title: Specific effect of zinc ions on DNA polymerase activity of avian myeloblastosis virus.
    Author: Palan PR, Eidinoff ML.
    Journal: Mol Cell Biochem; 1978 Nov 01; 21(2):67-9. PubMed ID: 214695.
    Abstract:
    The effect of selected cations on DNA synthesis by DNA-polymerase of avian myeloblastosis virus (AMV) was studied. Zinc ions at low concentration (0.2mM) in the assay system enhanced the activity about 2 x fold and at higher concentration (2.0 mM) inhibited the activity completely. In contrast, addition of lithium and potassium salts produced inhibitory effects in this ionic concentration range. Replacement of K+ ion had an inhibitory effect on the activity.
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