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  • Title: Fluorescence-enhanced potassium ions detection based on inherent quenching ability of deoxyguanosines and K(+)-induced conformational transition of G-rich ssDNA from duplex to G-quadruplex structures.
    Author: Zhang Y, Tian J, Zhai J, Luo Y, Wang L, Li H, Sun X.
    Journal: J Fluoresc; 2011 Sep; 21(5):1841-6. PubMed ID: 21472444.
    Abstract:
    Herein, we develop a novel single fluorophore-labeled double-stranded oligonucleotide (OND) probe for rapid fluorescence-enhanced K(+) detection, based on an inherent quenching ability of guanine bases and G-rich OND conformation transition from duplex to G-quadruplex. This probe presents high sensitivity and good selectivity for the detection of K(+), and the assay process is simple and fast.
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