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  • Title: Salivary duct carcinoma of the parotid.
    Author: Pons Y, Alves A, Clément P, Conessa C.
    Journal: Eur Ann Otorhinolaryngol Head Neck Dis; 2011 Sep; 128(4):194-6. PubMed ID: 21474417.
    Abstract:
    INTRODUCTION: Salivary duct carcinoma is one of the rarest and most aggressive forms of parotid tumor. We report two cases. CASES: Case 1: a 78-year-old man was referred for a salivary duct carcinoma of the left parotid gland. Treatment was surgical (parotidectomy with ipsilateral selective neck dissection), without capsule rupture, and with healthy margins. At seven years' follow-up, the patient was alive and disease-free. Case 2: a 41-year-old man was referred for a salivary duct carcinoma of the left parotid gland. Parotidectomy with ipsilateral selective neck dissection left healthy but insufficient margins (<1 cm), and postoperative radiation therapy (70 Gy) was undertaken. At eight years' follow-up, the patient was alive and free of recurrence. DISCUSSION: Mean patient age in the literature is 60 years, with a male-to-female ratio of 2:1. Mean five-years' recurrence-free survival was 34%. CONCLUSION: Surgery is the main form of treatment in this indication. Postoperative radiation therapy is indicated in case of extraparotid extension, pathological resection margins, cervical lymph node metastasis, lymphatic embolus and/or neurologic invasion. Chemotherapy is generally reserved for metastatic forms of the disease.
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