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  • Title: The effect of nitrous oxide on intracuff pressure of the size 2 ProSeal Laryngeal Mask Airway.
    Author: Chen BZ, Luo LH, Jiang L, Wang RR, Li J, Tan L.
    Journal: J Clin Anesth; 2011 May; 23(3):214-7. PubMed ID: 21489770.
    Abstract:
    STUDY OBJECTIVE: To investigate intracuff pressure changes in the ProSeal Laryngeal Mask Airway (PLMA) during 50% nitrous oxide (N₂O) anesthesia. DESIGN: Prospective, randomized study. SETTING: Operating room of a university-affiliated hospital. PATIENTS: 40 ASA 1 and 2 children, aged 2 to 6 years, weighing 10-20 kg, undergoing elective inguinal herniorrhaphy with general anesthesia. INTERVENTIONS AND MEASUREMENTS: Patients were assigned to two groups (n = 20). Patients in Group A were anesthetized with 50% N(2)O in oxygen and sevoflurane, while patients in Group B were anesthetized with 50% air in oxygen and sevoflurane. PLMA cuffs were inflated with air. PLMA intracuff pressures starting from a baseline pressure of 30 mmHg were recorded using a pressure transducer for 30 minutes. The occurrence of postoperative throat discomfort was recorded. MAIN RESULTS: In Group A, who inhaled 50% N₂O for 30 minutes, intracuff pressures reached 86.7 ± 10.4 mmHg, while in Group B, who inhaled 50% air for 30 minutes, intracuff pressures were 29.7 ± 1.0 mmHg. The postoperative throat complication rate in Group A was 45%, which was significantly higher than in Group B (5%). CONCLUSION: PLMA intracuff pressure increased significantly during 50% N₂O anesthesia. The children's postoperative throat complication rate also was increased.
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