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  • Title: Suction blister epidermal grafting using a modified suction method in the treatment of stable vitiligo: a retrospective study.
    Author: Li J, Fu WW, Zheng ZZ, Zhang QQ, Xu Y, Fang L.
    Journal: Dermatol Surg; 2011 Jul; 37(7):999-1006. PubMed ID: 21492308.
    Abstract:
    BACKGROUND: Of various surgical therapies used for the replenishment of melanocytes in recalcitrant and stable vitiligo, suction blister epidermal grafting (SBEG) is one of the simplest and most effective methods. OBJECTIVE: To evaluate the effectiveness and potential complications of SBEG in the treatment of stable vitiligo through the use of a modified dermis-epidermis separator designed by the authors. MATERIALS AND METHODS: One thousand one hundred people with stable vitiligo unresponsive to other medical treatments were treated with SBEG therapy. The negative pressure generated by the dermis-epidermis separator raised blisters at recipient and donor sites. Repigmentation was assessed 6 months after epidermis transplantation. RESULTS: Complete repigmentation was observed in 227 patients (20.6%), and excellent repigmentation (>50%) was observed in 568 (51.6%)-a success rate of 72.3%. No superficial scarring was observed at the grafted or donor sites, and no serious complications were encountered. CONCLUSION: SBEG is an established, simple, and effective treatment for resistant and stable vitiligo. Patients suffer few complications and are receptive to this type of therapy.
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