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  • Title: Value of T2-weighted MR imaging in differentiating low-fat renal angiomyolipomas from other renal tumors.
    Author: Choi HJ, Kim JK, Ahn H, Kim CS, Kim MH, Cho KS.
    Journal: Acta Radiol; 2011 Apr 01; 52(3):349-53. PubMed ID: 21498374.
    Abstract:
    BACKGROUND: Accurate preoperative diagnosis of fat scanty angiomyolipomas is an important clinical issue. By evaluating the low signal intensity of angiomyolipomas in MR T2-weighted images the diagnostic accuracy can be elevated. PURPOSE: To retrospectively assess the usefulness of T2-weighted MR imaging for differentiating low-fat angiomyolipomas (AMLs) from other renal tumors. MATERIAL AND METHODS: We retrospectively evaluated 71 patients with surgically proven renal masses (10 AMLs, 57 renal cell carcinomas [RCCs], and four oncocytomas), all of which showed no visible fat as well as gradual enhancement patterns on contrast-enhanced CT. Signal intensity was measured in each renal mass and in the spleen on T2-weighted images, and each signal intensity ratio (SIR) was calculated; SIR values were then compared in the AML and non-AML groups. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performance of the two parameters for differentiating the two groups. RESULTS: The SIR values (77 ± 24% vs. 162 ± 79%, p = 0.002) were significantly lower in the AML than in the non-AML group. The area under the ROC curve was 0.926 for SIR. The sensitivity and specificity in the diagnosis of AMLs were 90% and 90.2%, using SIR cut-off of 92.5%. CONCLUSION: Signal intensity measurements on T2-weighted MR images can differentiate AML from non-AML in the kidney.
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