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  • Title: [Various characteristics of the contractile function of the heart in cardiac hypertrophy during readaptation after adaptation of the body to high-altitude hypoxia].
    Author: Varosian MA, Martirosian MF, Tatinian NG, Petrosian VP.
    Journal: Kosm Biol Aviakosm Med; 1990; 24(6):42-5. PubMed ID: 2149867.
    Abstract:
    Hemodynamics, coronary circulation, electric activity and morphologic changes of the heart were investigated in 150 rabbits after their extended adaptation to high altitude hypoxia and during readaptation. It was found that changes in the contractile function of the hypertrophied heart, which developed as a result of moderate hypertrophy and isotonic hyperfunction of the left ventricle and marked hypertrophy and isometric hyperfunction of the right ventricle during prolonged adaptation to hypoxia, recovered within 15-30 days after hypoxia exposure was discontinued.
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