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  • Title: Gusanlungionosides A-D, potential tyrosinase inhibitors from Arcangelisia gusanlung.
    Author: Yu LL, Hu WC, Ding G, Li RT, Wei JH, Zou ZM, Wang MH.
    Journal: J Nat Prod; 2011 May 27; 74(5):1009-14. PubMed ID: 21500777.
    Abstract:
    Four new megastigmane glycosides, named gusanlungionosides A-D (1-4), together with 10 known compounds (5-14), were isolated from the stems of Arcangelisia gusanlung. The structures and absolute configurations of 1-4 were elucidated by comprehensive analysis of their NMR and CD data. Compounds 1-4 exhibited strong inhibitory effects not only on the mushroom tyrosinase activity in vitro but also on melanogenesis in cells.
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