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  • Title: [Further development of P. multocida vaccines for swine].
    Author: Schimmel D.
    Journal: Berl Munch Tierarztl Wochenschr; 1990 Dec 01; 103(12):410-1. PubMed ID: 2150307.
    Abstract:
    149 strains with antigen fractions of both A and D type could be found out of 446 P. multocida field strains of porcine origin. Most of them are producing the dermonecrotizing toxin. These A/D strains proved to be virulent in mice and piglets as well. In mice, the vaccination with one of the most virulent and immunogenic A/D strains, inactivated and A1(OH)3 adsorbed caused an immunity against challenge infections with P. multocida of types A, D and A/D. This effect could be confirmed on SPF piglets.
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