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  • Title: [The treatment of bacterial infections of the lower respiratory tract in childhood. An open comparative study of sulbactam/ampicillin vs. ceftazidime].
    Author: Longo L, Pugliese A, Schiavone R, Fumarola L, Federici S, De Lucia MG, Canale MP.
    Journal: Clin Ter; 1990 Dec 15; 135(5):373-7. PubMed ID: 2150368.
    Abstract:
    Sixty children suffering from lower respiratory tract infections have been included into this study, respectively 30 (18 M + 12 F) in the sulbactam/ampicillin (S/A) group and 30 (20 M + 10 F) in the ceftazidime (CFT) group. Average age was 42.9 months +/- 34.4 in S/A group (range 6-120) and 48.7 +/- 42.1 (range 6-144) in CFT group. Both groups were similar as to sex, age, type and duration of the infection. Posology was 150 mg/kg/die for S/A and 50 mg/kg/die for CFT. The duration of treatment was 7.2 days +/- 2.2 (range 5-12) for S/A group and 6.4 days +/- 1.6 (range 5-12) for CFT group. At the end of the therapy clinical recovery has been obtained in all cases. A rapid defervescence and remission of symptoms at an identical rate has been recorded in both treatment groups. General and local tolerability was excellent in both treatment groups.
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