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  • Title: Antiasthmatic versus surgical treatment-how important is the precise analysis of spirometry?
    Author: Swiebocka E, Siergiejko P, Grygorczuk A, Siergiejko Z.
    Journal: J Asthma; 2011 May; 48(4):341-4. PubMed ID: 21504348.
    Abstract:
    OBJECTIVE: Carcinoids are low-grade, slow growing malignant tumors in the bronchi usually producing symptoms secondary to bronchial obstruction. We describe a case of 25-year-old woman who was initially diagnosed with asthma. METHOD: Case report. RESULTS: Because of exacerbation and unresponsiveness to proper asthma treatment she was referred to spirometry, which showed low values of forced expiratory volume in 1 second. The shape of inspiratory limb of flow volume curve suggested an obstruction in the main bronchus or in the trachea. Further bronchoscopy revealed a tumor of the right main bronchus with characteristic histological features for carcinoid. CONCLUSIONS: Both the inspiratory curve and the expiratory part of the flow-volume loop should be evaluated in patients being evaluated for asthma. If there are changes in the shape of the inspiratory limb suggesting an obstruction, CT and/or bronchoscopy should be considered.
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