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  • Title: [Effect of water immersion on glucose, insulin and atrial natriuretic factor levels in patients with transplanted heart].
    Author: Kokot F, Religa Z, Pasyk S, Grzeszczak W, Wiecek A, Frycz J, Bochenek A.
    Journal: Kardiol Pol; 1990; 33(11-2):16-21. PubMed ID: 2151394.
    Abstract:
    In 6 heart transplant patients [HTP] and in 10 healthy subjects the influence of water immersion [WI] on blood levels of glucose, insulin and atrial natriuretic peptide [ANP] were studied. HTP showed significantly higher baseline ANP levels and a reduced response of ANP to water immersion as compared with normals. HTP did not differ from normals by baseline plasma levels of glucose and insulin. WI induced significant decline of blood glucose and increase of insulin in both examined groups. A significant correlation was found between WI induced increase of blood insulin and ANP and between the increase of ANP and decline of blood glucose both in HTP and in healthy subjects. Data presented in this paper suggest existence of a significant relationship between ANP and insulin secretion and participation of ANP in the carbohydrate metabolism both in normals and HTP.
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