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Title: Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome: a new indication for propranolol treatment. Author: Hermans DJ, van Beynum IM, van der Vijver RJ, Kool LJ, de Blaauw I, van der Vleuten CJ. Journal: J Pediatr Hematol Oncol; 2011 May; 33(4):e171-3. PubMed ID: 21516018. Abstract: Kaposiform hemangioendothelioma is a rare vascular tumor in children. Especially, in association with the Kasabach-Merritt Phenomenon it can be life threatening. The management of these patients is very difficult and an aggressive treatment regime is required. Several multimodality and chemotherapeutic regimens have been described but with variable success and many side effects. We present a 6-week-old boy with Kaposiform hemangioendothelioma and Kasabach-Merritt Phenomenon. Ongoing propranolol treatment with only 4 initial courses of vincristine resulted in a remission that lasted at least 1 year.[Abstract] [Full Text] [Related] [New Search]