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  • Title: Validation of optical low coherence reflectometry retinal and choroidal biometry.
    Author: Read SA, Collins MJ, Alonso-Caneiro D.
    Journal: Optom Vis Sci; 2011 Jul; 88(7):855-63. PubMed ID: 21516051.
    Abstract:
    PURPOSE: To compare measurements of retinal thickness (RT) and choroidal thickness (ChT) obtained with an optical low coherence reflectometry (OLCR) biometer (Lenstar LS 900) with those obtained with a spectral domain optical coherence tomographer (SD OCT) (Copernicus SOCT HR) in young normal subjects. METHODS: Twenty young adult subjects had foveal RT and subfoveal ChT measurements obtained with OLCR biometry and SD OCT. RT and ChT was derived through manual analysis of A-scan data from the OLCR biometer. An average SD OCT foveal B-scan image derived from a series of 50 multiple B-scans was also analyzed to determine RT and ChT for each subject. Measurements from the two instruments were compared using Pearson correlation and Bland-Altman analysis. RESULTS: RT and ChT measurements from the two instruments were highly correlated (r of 0.80 and 0.94, respectively, p<0.0001). The mean RT with SD OCT and OLCR were 195 ± 17 μm and 196 ± 16 μm, respectively (mean difference, 1 ± 8 μm). The mean ChT was 324 ± 71 μm and 328 ± 84 μm with SD OCT and OLCR, respectively (mean difference, 4 ± 24 μm). CONCLUSIONS: Foveal RT and subfoveal ChT measures from OLCR biometry exhibit a strong correlation and good agreement with measures derived from SD OCT in a population of young adult subjects.
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