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  • Title: Isoniazid-induced pellagra.
    Author: Bilgili SG, Karadag AS, Calka O, Altun F.
    Journal: Cutan Ocul Toxicol; 2011 Dec; 30(4):317-9. PubMed ID: 21517721.
    Abstract:
    Pellagra is characterized by dermatitis, diarrhea, dementia and eventually death occurring as a result of niacin or its precursor tryptophan deficiency. Although pellagra is a well-known complication of isoniazid (INH) therapy, the clinical diagnosis may be missed or delayed that may cause life-threatening consequences. Due to the diversity of pellagra-related signs and symptoms, the diagnosis can be made with an appropriate index of suspicion. We report a 7-year-old boy presenting with INH-induced pellagra that resolved after the administration of the niacin therapy.
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