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  • Title: Daphnane-type diterpenoids from Trigonostemon howii.
    Author: Dong SH, Zhang CR, Xu CH, Ding J, Yue JM.
    Journal: J Nat Prod; 2011 May 27; 74(5):1255-61. PubMed ID: 21520897.
    Abstract:
    Nine new daphnane-type diterpenoids (1-9), named trigohownins A-I, and four known analogues were isolated from Trigonostemon howii. Their structures were elucidated on the basis of extensive NMR and MS analyses. Trigohownins A (1) and D (4) exhibited moderate cytotoxic activity against the HL-60 tumor cell line, with IC50 values of 17.0 and 9.3 μM, respectively.
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