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  • Title: Overview of thymosin activity.
    Author: Marshall GD, Low TL, Thurman GB, Hu SK, Rossio JL, Trivers G, Goldstein AL.
    Journal: Cancer Treat Rep; 1978 Nov; 62(11):1731-7. PubMed ID: 215305.
    Abstract:
    Our current research program centers around the biologic and chemical characterization of the family of polypeptides present in thymosin fraction 5. A system of nomenclature has been developed and the peptides are being systematically isolated and chemically characterized. Thymosin fraction 5 and its component parts influence a variety of lymphocyte properties including cyclic nucleotide levels, migration inhibitory factor production, T-dependent antibody production, and expression of certain surface markers. Thymosin is being used in clinical trials to investigate its effects on immunodeficiency diseases, malignant diseases, and autoimmune diseases.
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